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Thyroid Interference : L-Carnitine may reduce thyroid hormone activity, so those with hypothyroidism should consult a doctor

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PPARs as master regulators of carnitine homeostasis Genes regulated by peroxisome proliferator-activated receptor (PPAR) are involved in many biological processes such as fatty acid catabolism, ketogenesis and gluconeogenesis, and also play a key role in the regulation of carnitine homeostasis [189]

This means you can tweak the dosage to match exactly what your body needs, whether its a little boost or a major overhaul, making it as personal as your morning coffee order